Congenital diaphragmatic hernia (CDH) is one of the most challenging diagnoses in the NICU, demanding rapid decision-making, coordinated teamwork, and a deep understanding of physiology. In this episode of NANNcast, Dr. Jamie Gilley unpacks the full clinical journey of CDH – from prenatal markers and imaging, to delivery room stabilization, ventilation strategies, pulmonary hypertension and sedation management, surgical repair, and long-term follow-up.